WHO announces cure for excessive bleeding after childbirth
The World Health Organisation in
collaboration with Ferring and MSD for Mothers, has announced that
heat-stable carbetocin is as effective as oxytocin in preventing
excessive bleeding following vaginal birth.
Researched and developed by Ferring,
heat-stable carbetocin remains effective at high temperatures, an answer
to the limitation of oxytocin which must be stored and transported at 2
– 8°C.
According to WHO, every year, 14 million
women are affected by postpartum haemorrhage and this is the leading
cause of maternal death worldwide, causing approximately 70,000 deaths
per year. It remains a major cause of maternal death in Nigeria.
The clinical study was conducted by the
WHO Department of Reproductive Health and Research including the UNDP,
UNFPA UNICEF, World Bank Special Programme of Research and Development
and Research Training in Human Reproduction, using Ferring’s heat-stable
carbetocin.
The Chief Medical Officer, Ferring
Pharmaceuticals, Prof. Klaus Dugi, said, “This is an important step
forward in postpartum haemorrhage prevention and these results pave the
way for heat- stable carbetocin to potentially save the lives of
thousands of women, especially in areas where cold-chain transport and
storage is not feasible.
“We will now work with the WHO and MSD
for mothers to make heat- stable carbetocin available in countries where
it is needed most, protecting women and families around the world.”
Studies in Nigeria and other developing
countries have revealed degradation and loss of efficacy in oxytocin
ampoules, which could be due to inadequate storage and distribution
conditions, hence the need for the heat-stable carbetocin product.
Data showed that heat-stable carbetocin
maintains effectiveness for at least three years at 30°C and six months
at 40°C and has the potential to save thousands of women’s lives in
Nigeria and other low- and lower-middle income countries, where 99% of
postpartum haemorrhage related deaths occur and where the refrigeration
of medicines can be difficult to achieve and maintain.
The WHO publication concludes that the
study should inform care in countries where cold-chain transport and
storage of medicines was difficult to achieve and was a barrier to
effective postpartum haemorrhage prevention.
Culled from Punch .com
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